Novel antibacterial nanofibrous PLLA scaffolds
نویسندگان
چکیده
منابع مشابه
Nanofibrous scaffolds in biomedical applications
Nanofibrous scaffolds are artificial extracellular matrices which provide natural environment for tissue formation. In comparison to other forms of scaffolds, the nanofibrous scaffolds promote cell adhesion, proliferation and differentiation more efficiently due to having high surface to volume ratio. Although scaffolds for tissue engineering have been fabricated by various techniques but elect...
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The development of nano-sized scaffolds with antibacterial properties that mimic the architecture of tissue is one of the challenges in tissue engineering. In this study, polycaprolactone (PCL) and PCL/gelatine (Ge) (70:30) nanofibrous scaffolds were fabricated using a less toxic and common solvent, formic acid and an electrospinning technique. Nanofibrous scaffolds were coated with silver (Ag)...
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The discipline of tissue engineering opens up the ways for repair and regenerate damaged organs and tissues. In the current work biomimetic nanofibrous scaffolds were fabricated by electrospinning. Poly-L-lactic acid (PLLA) was blended with collagen and gelatin to fabricate PLLLA-collagen and PLLA-gelatin fibrous scaffolds respectively. Pure PLLA and gelatin scaffolds served as controls. All th...
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The fibrocartilaginous menisci dwell between the articular surfaces of the knee and play a central role in joint function. Damage through trauma or degenerative changes is a common orthopaedic injury, disrupts the meniscus mechanical function, and leads to the precocious development of osteoarthritis. The current standard of treatment is removal of the damaged tissue, a procedure that does not ...
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Statement of Purpose: Corneal blindness deprives 10 million people worldwide of their sight. Current treatments for corneal blindness mainly rely on implants that replace the injured tissue and have been clinically unsuccessful thus far. The goal of this project is to prevent corneal blindness by developing clinically-viable scaffolds that promote orderly corneal wound healing using biochemical...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2010
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2010.05.035